Polygonum cuspidatum extract, Gentrin Knotweed P.E, Polygonum cuspidatum Sieb.et Zucc. P.E.

Functions: 1.Antipyretic and analgesic effects 2.prevent heart and liver damage

Polygonum cuspidatum Sieb.et Zucc.P.E.

English name: Polygonum cuspidatum Sieb.et Zucc. P.E.

Latin name: Rhizoma Et Radix Polygoni Cuspidati

Source: dry rhizome and root of Polygonum cuspidatum, Polygonaceae

The main components

Resveratrol and emodin. Studies shows that resveratrol and emodin show a wide range of antioxidant properties, such as LDL cholesterol oxidation and lipid peroxidation. Resveratrol also shows that it's good for cardiovascular health and blood circulation; relieving pain, clearing heat and dehumidification, detoxification expectorant. Other ingredients: Dan anthrone, emodin, and rhein, they have anti-inflammatory, anti-arthritis and antimicrobial activity

Antipyretic and analgesic effectsResveratrol plays therapeutic efficacy through a variety of different ways, it shows a certain antipyretic and analgesic activity. It shows that the extract entrusts gastric mucosa the ability of stress ulcer which is caused by gastric secretion suppressed without effecting on blood pressure.

2 Anticancer and antimutagenicity

Resveratrol shows ability in cancer chemoprevention as antioxidant, anti-mutagen and anti-inflammatory agent. At the same time it can induce human promyelocytic leukemia cells (anti-proliferative effect) and the inhibition of the development of breast cancer prior structure lesion. Resveratrol can also inhibit protein tyrosine kinase which catalysises tyrosine phosphorylation.The kinase is contained in caryokinesis. Making use of resveratrol’s inhibiting protein tyrosine kinasefunction can   produce antimutagenicity function by preventing anti-mutagenic effect.

To prevent heart and liver damage

Resveratrol can inhibit deposition of the liver triglyceride and

cholesterol. And it also promote alanine aminotransferase a

nd aspartate aminotransferase levels’ increasement by inhibiting

the peroxidation of liver fat. And the analysis of two enzymes

show good diagnostic information to heart and liver damage

Antithrombotic function

Resveratrol can inhibit the synthesis of lipoxygenase, the enzyme exists in leukocyte, heart, brain, lung and spleen. Thus resveratrol prevents the formation of blood clots in blood vessels. And it also can inhibit platelet’s concentration after treatment of clonidine which is antihypertensive drug.

To enhance the immune system activity on treatment of wound

Resveratrol can also strengthen the immune system and promote healing of burn.

Dose: 1-3 times daily doses, the total daily dose should be 50-80 mg.

Chemical components:

The product is mainly composed of resveratrol and emodin, chemical structure is as following: Resveratrol C14H12O3

Emodin C15H10O5

Quality

Ratio: 50%

Used part: rhizome and root

Color: brown

Appearance: powder

Mesh: 80 mesh

Odor: characteristic smell

Loss on drying: ≤ 5%

Ash: <5%

Heavy metals: <10PPM

Pesticide residue: <2PPM

Microbiological standard

Total amount of bacteria: <1000CFU/gm

E. coli: not detected  

Salmonella: not detected  

Fungi and yeast:<100CFU/gm

Storage: stored in cool and dry place, protected from light, avoiding heat.

Shelf life:2 years

Packing:double-layer plastic bag for internal use, aluminum foil bags or cardboard for external use (25 kg / barrel).

Polygonum cuspidatum extract, Gentrin Knotweed P.E, Polygonum cuspidatum Sieb.et Zucc. P.E.